Mga tagagawa at supplier ng China Doxycycline Hyclate

Doxycycline Hyclate

Maikling Paglalarawan:

Pangalan ng API	Indikasyon	Pagtutukoy	US DMF	EU DMF	CEP
Doxycycline Hyclate	Antibiotics	USP/EP	13771	√

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Background

Ang Doxycycline hyclate ay isang antibiotic [1].

Ang Doxycycline hyclate ay isang derivative ng tetracycline at nagtataglay ng mga aktibidad ng anti-inflammatory at antimicrobial. Pinipigilan ng Doxycycline ang pagtitiklop ng dengue virus sa vitro sa paraang nakadepende sa temperatura. Ang halaga ng IC50 ay 52.3μM sa 37°C at 26.7μM sa 40°C. Pinipigilan nito ang dengue virus sa pamamagitan ng pagpigil sa NS2B-NS3 serine protease ng virus. Binabawasan ng 60μM doxycycline ang CPE ng mga cell na nahawahan ng DNEV2 [1].

Ang Doxycycline ay natagpuan na isang inhibitor ng MMP. Ang paggamot sa doxycycline ay binabawasan ang mga antas ng MMP-8 at -9 at pinipigilan ang pagpapahayag ng tissue na MMP-2 at MMP-9. Bukod dito, ang paggamot na may doxycycline ay makabuluhang binabawasan ang saklaw ng intracranial aneurysms. Ang Doxycycline ay naiulat din na isang anti-inflammatory agent batay sa pagsugpo nito sa matrix metalloproteinases. Bilang karagdagan, ang doxycycline ay may makapangyarihang aktibidad na antimalarial na may halaga ng IC50 na 320nM sa 96h in vitro [2, 3].

Mga sanggunian:
[1] Rothan HA, Mohamed Z, Paydar M, Rahman NA, Yusof R. Inhibitory effect ng doxycycline laban sa dengue virus replication in vitro. Arko Virol. 2014 Abr;159(4):711-8.
[2] Maradni A, Khoshnevisan A, Mousavi SH, Emamirazavi SH, Noruzijavidan A. Tungkulin ng matrix metalloproteinases (MMPs) at MMP inhibitors sa intracranial aneurysms: isang review na artikulo. Med J Islam Repub Iran. 2013 Nob;27(4):249-254.
[3] Draper MP, Bhatia B, Assefa H, Honeyman L, Garrity-Ryan LK, Verma AK, Gut J, Larson K, Donatelli J, Macone A, Klausner K, Leahy RG, Odinecs A, Ohemeng K, Rosenthal PJ, Nelson ML. In vitro at in vivo antimalarial efficacies ng optimized tetracyclines. Mga Ahente ng Antimicrob Chemother. 2013 Hul;57(7):3131-6.

Paglalarawan

Ang Doxycycline (hyclate) (Doxycycline hydrochloride hemiethanolate hemihydrate), isang antibiotic, ay isang oral active at broad-spectrum metalloproteinase (MMP) inhibitor[1].

Klinikal na Pagsubok

Numero ng NCT	Sponsor	Kundisyon	Petsa ng Pagsisimula	Phase
NCT00246324	Louisiana State University Health Sciences Center Shreveport\|Biogen	Multiple sclerosis	Disyembre 2003	Phase 4
NCT00910715	University Medical Center Ljubljana	Erythema Chronicum Migrans	Hunyo 2009	Hindi Naaangkop
NCT00243893	University of California, San Francisco\|National Institute of Neurological Disorders and Stroke (NINDS)	Aneurysms\|Mga Arteriovenous Malformations	Hulyo 2004	Phase 1
NCT00126399	CollaGenex Pharmaceuticals	Rosacea	Hunyo 2004	Phase 3
NCT01318356	Radboud University\|ZonMw: The Netherlands Organization for Health Research and Development	Q Fever\|Fatigue Syndrome, Chronic\|Coxiella Infection	Abril 2011	Phase 4
NCT00177333	Unibersidad ng Pittsburgh	Aborsyon, Sapilitan\|Pagsusuka	Setyembre 2005	Phase 4
NCT00007735	US Department of Veterans Affairs\|Pfizer\|United States Department of Defense\|VA Office of Research and Development	Persian Gulf Syndrome\|Mga Impeksyon sa Mycoplasma	Enero 1999	Phase 3
NCT00351273	University of South Florida\|National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)	Arthritis, Reactive\|Reiter Disease	Mayo 2006	Phase 3
NCT00469261	Ospital ng Careggi	Myocardial Infarction\|Pag-remodel ng Kaliwang Ventricular	Mayo 2007	Phase 2
NCT00547170	Unibersidad ng Pittsburgh\|Tu Du Hospital	Endometritis	Enero 2007	Phase 4
NCT01475708	University Medical Center Ljubljana	Lyme Borreliosis	Mayo 2011
NCT01368341	Morten Lindbaek\|Norwegian Institute of Public Health\|Sorlandet Hospital HF\|Norwegian University of Life Sciences\|University of Oslo	Erythema Migrans\|Erythema Chronicum Migrans\|Borreliosis\|Lyme Disease\|Maagang Lyme Disease	Hunyo 2011	Phase 4
NCT02538224	Unibersidad ng Islamikong Azad, Tehran	Talamak na Periodontitis	Hulyo 2013	Phase 2\|Phase 3
NCT00066027	Unibersidad ng Nebraska\|National Institute of Dental and Craniofacial Research (NIDCR)	Periodontitis	Hunyo 2002	Phase 3
NCT00376493	Hospital de Clinicas de Porto Alegre	Septic Abortion	Mayo 2006	Phase 4
NCT03448731	Fundacion CRIS de Investigación para sa Vencer el Cáncer\|Amgen\|Apices Soluciones SL	Pagkalason sa Balat	Mayo 10, 2018	Phase 2
NCT00989742	Unibersidad ng Nottingham	Lymphangioleiomyomatosis\|Tuberous Sclerosis	Hulyo 2009	Phase 4
NCT01438515	Horizon Health Network	Staphylococcus Aureus na lumalaban sa methicillin	Agosto 2008	Hindi Naaangkop
NCT02929121	Ang Task Force for Global Health\|United States Agency for International Development (USAID)	Lymphedema\|Lymphatic Filariasis\|Filariasis	Enero 15, 2019	Phase 3
NCT00952861	Odense University Hospital\|Kolding Sygehus\|Svendborg Hospital\|Fredericia Hospital\|Naestved Hospital\|Hillerod Hospital, Denmark\|Region Syddanmark\|Danmarks Lungeforening\|Danish National Research Foundation	Sakit sa Pulmonary, Talamak na Nakahahadlang	Oktubre 2009	Phase 4
NCT00138801	Sorlandet Hospital HF	Lyme Neuroborreliosis	Marso 2004	Phase 3
NCT00942006	University Medical Center Ljubljana	Pinaghihinalaang Maagang Lyme Neuroborreliosis	Hulyo 2009	Hindi Naaangkop
NCT02713607	Unibersidad ng California, Davis	Acne Vulgaris	Marso 2016	Phase 1\|Phase 2
NCT00560703	Galderma	Blepharitis\|Meibomianitis\|Tuyong Mata	Nobyembre 2007	Phase 2
NCT01014260	Johns Hopkins University	Sakit sa Cardiovascular	Setyembre 2010	Phase 4
NCT00000938	National Institute of Allergy and Infectious Diseases (NIAID)	Sakit na Lyme		Phase 3
NCT01398072	University College, London\|Royal Free Hampstead NHS Trust\|University of Cambridge\|National Institute for Health Research, United Kingdom	Chronic Obstructive Pulmonary Disease (COPD).	Disyembre 2011	Phase 3
NCT03479502	Vanderbilt University Medical Center\|Orthopedic Research and Education Foundation	Adhesive Capsulitis\|Adhesive Capsulitis ng Hindi Natukoy na Balikat\|Frozen Shoulder	Enero 5, 2018	Phase 4
NCT02929134	Ang Task Force for Global Health\|United States Agency for International Development (USAID)	Lymphedema\|Lymphatic Filariasis\|Filariasis	Pebrero 16, 2018	Phase 3
NCT00480532	Oregon Health and Science University	Mga Contraceptive, Oral	Mayo 2007	Hindi Naaangkop
NCT01594827	Johns Hopkins University\|Case Western Reserve University\|Cystic Fibrosis Foundation	Cystic fibrosis	Oktubre 2012	Phase 2
NCT01744093	Weill Medical College ng Cornell University\|National Heart, Lung, and Blood Institute (NHLBI)	HIV\|Chronic Obstructive Pulmonary Disease (COPD)\|Emphysema	Hulyo 17, 2014	Hindi Naaangkop
NCT03530319	Ospital ng Pamantasang Pambansang Taiwan	Pneumonia, Mycoplasma	Nobyembre 10, 2018	Hindi Naaangkop
NCT04167085	Unibersidad ng California, Los Angeles	Epistaxis	Disyembre 18, 2017	Phase 4
NCT01411202	Ottawa Hospital Research Institute	Malignant Pleural Effusion	Hunyo 2011	Phase 2
NCT01474590	Galderma	Acne	Nobyembre 2011	Phase 3
NCT00649571	Mylan Pharmaceuticals	Malusog	Hulyo 2005	Phase 1
NCT02899000	Galderma Laboratories, LP	Acne Vulgaris	Hulyo 29, 2016	Phase 4
NCT00538967	Leiden University Medical Center	Aortic Aneurysm, Tiyan	Mayo 2002	Phase 2
NCT00439400	Alacrity Biosciences, Inc.	Tuyong Mata	Pebrero 2007	Phase 2
NCT00917553	Thomas Gardner\|Penn State University\|Juvenile Diabetes Research Foundation\|Milton S. Hershey Medical Center	Diabetic Retinopathy	Hulyo 2009	Phase 2
NCT00495313	CollaGenex Pharmaceuticals	Rosacea	Marso 2007	Phase 4
NCT01855360	Brigham at Women's Hospital	amyloidosis; Puso (Pagpapakita)\|Senile Cardiac Amyloidosis	Hunyo 2013	Phase 1\|Phase 2
NCT00419848	Shahid Beheshti University of Medical Sciences	Acne	Agosto 2006	Phase 2
NCT03532464	Ospital ng Unibersidad, Bordeaux\|USC EA 3671 Ang mga impeksyon ay humahantong sa mycoplasmes at chlamydiae	Impeksiyon ng Chlamydia Trachomatis\|Impeksyon sa Puwerta\|Impeksyon sa Puwit	Hulyo 1, 2018	Phase 4
NCT02756403	Medstar Health Research Institute\|Society of Family Planning	First Trimester Abortion	Marso 2016	Hindi Naaangkop
NCT00353158	National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)\|National Institutes of Health Clinical Center (CC)	Mga Malusog na Volunteer\|Mga Impeksyon sa Fungal\|Mga Impeksyon sa Bakterya	Hulyo 11, 2006	Phase 1
NCT01317433	Institut Cancerologie de l'Ouest	Colorectal Cancer Metastatic\|Toxicity sa Balat	Disyembre 2010	Phase 3
NCT01658995	Petra M. Casey\|Mayo Clinic	Pagdurugo na nauugnay sa ESI	Setyembre 13, 2012	Phase 3
NCT03968562	State University of New York - Downstate Medical Center	Mga pantal	Mayo 15, 2019	Phase 2
NCT02569437	Icahn School of Medicine sa Mount Sinai	Polyp ng Nasal Sinus	Setyembre 2014	Phase 2
NCT01198509	NYU Langone Health\|National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)\|Memorial Sloan Kettering Cancer Center	Rheumatoid Arthritis\|Psoriatic Arthritis\|Periodontal Disease	Enero 2010	Hindi Naaangkop
NCT01163994	University Medical Center Ljubljana	Maramihang Erythema Migrans	Hunyo 2010	Hindi Naaangkop
NCT02388477	Milton S. Hershey Medical Center	Pinsala ng Rotator Cuff		Hindi Naaangkop
NCT01010295	International Extranodal Lymphoma Study Group (IELSG)	Non-Hodgkin Lymphoma	Setyembre 2006	Phase 2
NCT00775918	Ranbaxy Laboratories Limited\|Ranbaxy Inc.	Malusog	Hunyo 2005	Hindi Naaangkop
NCT04050540	University of Washington\|Kenya Medical Research Institute\|Kenya National AIDS & STI Control Programme\|University of California, San Francisco\|National Institute of Allergy and Infectious Diseases (NIAID)	Mga Impeksyon sa HIV\|HIV+AIDS\|Impeksyon ng Neisseria Gonorrheae\|Impeksyon ng Chlamydia Trachomatis\|Impeksyon ng Syphilis	Pebrero 5, 2020	Phase 4
NCT02562651	Russian Academy of Medical Sciences	Mga Sakit sa Vascular\|Mga Sakit sa Cardiovascular\|Acute Myocardial Infarction	Pebrero 2014	Phase 2\|Phase 3
NCT00001101	National Institute of Allergy and Infectious Diseases (NIAID)	Sakit na Lyme		Phase 3
NCT00340691	National Institute of Allergy and Infectious Diseases (NIAID)\|National Institutes of Health Clinical Center (CC)	Mansonella Perstans Infection\|Mp Microfilaremia	Disyembre 6, 2004	Phase 2
NCT01112059	Unibersidad ng Alabama sa Birmingham\|Cystic Fibrosis Foundation	Cystic fibrosis	Nobyembre 2008	Hindi Naaangkop
NCT00652704	Par Pharmaceutical, Inc.\|Anapharm	Upang Matukoy ang Bioequivalence sa ilalim ng mga Kundisyon ng Fed	Hulyo 1999	Phase 1
NCT01783860	Tehran University of Medical Sciences	Posterior Blepharitis	Enero 2013	Phase 2
NCT02564471	State University of New York - Upstate Medical University\|Walter Reed Army Institute of Research (WRAIR)\|Kansas State University	Rabies	Abril 2016	Phase 4
NCT04206631	Unibersidad ng Indonesia	Acne Vulgaris	Abril 1, 2015	Phase 1
NCT03956446	University Medical Center Ljubljana\|University of Ljubljana School of Medicine, Slovenia	Tick Borne Encephalitis	Setyembre 1, 2014	Hindi Naaangkop
NCT03960411	Felix Chikita Fredy, MD\|National Cardiovascular Center Harapan Kita Hospital Indonesia\|Indonesia University	ST Elevation Myocardial Infarction\|Anterior Wall Myocardial Infarction\|Heart Failure\|Remodeling, Ventricular	Mayo 25, 2019	Phase 3
NCT00322465	National Institute of Allergy and Infectious Diseases (NIAID)	Urethritis	Nobyembre 2006	Phase 2
NCT01375491	University of California, San Diego\|Ruth L. Kirschstein National Research Service Award\|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)\|National Center for Research Resources (NCRR)	Type 2 Diabetes\|Obesity	Oktubre 2009	Phase 4
NCT03478436	Medikal na Unibersidad ng Vienna\|Dr. Reddy's Laboratories Limited	Rosacea	Hulyo 2016	Phase 1
NCT01207739	Radboud University\|Sint Maartenskliniek\|ZonMw: The Netherlands Organization for Health Research and Development	Lyme Disease\|Borrelia Infection	Setyembre 2010	Phase 4
NCT00939562	Pfizer	Impeksyon sa Bakterya	Nobyembre 2008	Phase 4
NCT03608774	National Institute of Allergy and Infectious Diseases (NIAID)	Impeksyon sa Anal Chlamydia	Hunyo 26, 2018	Phase 4
NCT02281643	Kwame Nkrumah University of Science and Technology\|University of Bonn\|Heinrich-Heine University, Duesseldorf	Mansonella Perstans Infection\|Buruli Ulcer\|Tuberculosis\|Co-infection	Oktubre 2014	Phase 2
NCT00066066	Ang Forsyth Institute\|National Institute of Dental and Craniofacial Research (NIDCR)	Periodontitis\|Mga Sakit sa Periodontitis	Hulyo 2003	Phase 2
NCT01798225	Medical University of South Carolina\|National Center for Research Resources (NCRR)	Sakit sa Periodontal\|Type 2 Diabetes Mellitus	Disyembre 2007	Phase 4
NCT00612573	Warner Chilcott	Acne Vulgaris	Pebrero 2008	Phase 2
NCT01631617	National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)\|National Institutes of Health Clinical Center (CC)	Eksema\|Dermatitis\|Mga Sakit sa Balat, Genetic\|Dermatitis, Atopic\|Mga Sakit sa Balat	Setyembre 18, 2012	Phase 2
NCT03173053	Radboud University\|ZonMw: The Netherlands Organization for Health Research and Development\|Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)\|Aalborg University Hospital\|Rigshospitalet, Denmark	Staphylococcus Aureus\|Karamdaman sa Paggalaw	Pebrero 8, 2018	Hindi Naaangkop
NCT00715858	McMaster University\|The Physicians' Services Incorporated Foundation	Sakit na Alzheimer	Mayo 2008	Phase 3
NCT03584919	University Medical Center Ljubljana	Erythema Chronicum Migrans	Hunyo 1, 2006	Hindi Naaangkop
NCT01469585	Unibersidad ng Hawaii\|Charles Drew Unibersidad ng Medisina at Agham\|Meharry Medical College	Pambihirang Pagdurugo	Nobyembre 2011	Hindi Naaangkop
NCT02759120	Weill Medical College of Cornell University\|Duke Clinical Research Institute\|University of Chicago\|University of Washington\|University of Pittsburgh\|National Heart, Lung, and Blood Institute (NHLBI)	Idiopathic Pulmonary Fibrosis	Marso 22, 2017	Phase 3
NCT02735837	Amirhossein Farahmand\|Islamic Azad University, Tehran	Diabetes Mellitus na May Sakit na Periodontal	Enero 2015	Phase 2\|Phase 3
NCT03655197	Unibersidad ng California, Davis	Rosacea\|Ocular Rosacea\|Cutaneous Rosacea	Nobyembre 2, 2017	Maagang Phase 1
NCT01188954	Northwell Health	Seroma	Enero 2010	Hindi Naaangkop
NCT00388778	Shahid Beheshti University of Medical Sciences	Acne\|Pamaga	Oktubre 2005	Phase 2\|Phase 3
NCT01087476	Metropolitan Autonomous University\|Instituto Nacional de Cancerologia de Mexico	Mucositis	Mayo 2010	Phase 2
NCT02174757	CD Pharma India Pvt. Ltd.\|Sree Mookambika Institute of Dental Sciences	Talamak na Periodontitis	Agosto 2014	Phase 3
NCT03911440	Ospital ng Pamantasang Pambansang Taiwan	Atypical Pneumonia	Nobyembre 10, 2018	Hindi Naaangkop
NCT02553083	Rabin Medical Center	Impeksyon sa Bakterya Dahil sa Helicobacter Pylori (H. Pylori)	Oktubre 22, 2015	Phase 4
NCT04234945	Ospital ng Pagtuturo sa Pamantasang Ahmadu Bello	Infertility, Babae\|Pelvic Inflammatory Disease	Enero 13, 2020	Hindi Naaangkop
NCT00892281	Galderma Laboratories, LP	Rosacea	Abril 2009	Phase 4
NCT02913118	Qingfeng Pharmaceutical Group	Community Acquired Pneumonia	Hulyo 2016	Phase 4
NCT04153604	Methodist Health System	Cirrhosis\|Spontaneous Bacterial Peritonitis	Nobyembre 4, 2019
NCT03153267	University Medical Center Ljubljana\|University of Ljubljana School of Medicine, Slovenia	Erythema Chronicum Migrans	Hunyo 1, 2017	Hindi Naaangkop
NCT03116659	James J. Peters Veterans Affairs Medical Center	Lymphoma, T-Cell, Cutaneous	Pebrero 1, 2018	Maagang Phase 1
NCT03401372	Jian Li\|Peking University First Hospital\|Chinese PLA General Hospital\|Beijing Chao Yang Hospital\|West China Hospital Affiliated with Sichuan University\|Tongji Hospital Affiliated with Tongji Medical College of HUST\|Union Hospital Affiliated with Tongji Medical College of HUST\|Shanghai Changzheng Hospital\| Nanfang Hospital ng Southern Medical University\|Peking Union Medical College Hospital	amyloidosis; Systemic	Abril 21, 2018	Hindi Naaangkop
NCT01380496	Par Pharmaceutical, Inc.\|Anapharm	Upang Matukoy ang Bioequivalence sa ilalim ng mga Kundisyon ng Fed	Nobyembre 1999	Phase 1
NCT03083197	Unibersidad ng Oxford\|Shoklo Malaria Research Unit\|Chiangrai Prachanukroh Hospital	Scrub Typhus	Oktubre 15, 2017	Phase 4
NCT00237016	Medical Corps, Israel Defense Force	Muling Lagnat, Tick-Borne\|Jarisch Herxheimer Reaction	Abril 2002	Phase 2\|Phase 3
NCT01308619	Galderma Laboratories, LP	Rosacea	Abril 2011	Phase 4
NCT01198912	Ospital ng Unibersidad, Ghent	Talamak na Rhinosinusitis\|Nasal Polyps	Nobyembre 22, 2011	Phase 2
NCT02016365	Unibersidad ng Umeå	Transthyretin Amyloidosis\|Cardiomyopathy	Pebrero 2012	Phase 2
NCT00783523	Unibersidad ng California, San Francisco	Arteriovenous Malformations\|Cavernous Angiomas\|Brain Aneurysms	Marso 2008	Phase 1
NCT03337932	University Medical Center Ljubljana	Erythema Chronicum Migrans	Enero 1, 2018	Hindi Naaangkop
NCT00568711	Dong-Min Kim\|Chosun University Hospital	Scrub Typhus	Setyembre 2006	Hindi Naaangkop
NCT01874860	Unibersidad ng Louisville\|James Graham Brown Cancer Center	Colorectal Cancer\|Ulo at Leeg na Kanser	Agosto 2013	Phase 2
NCT01171859	IRCCS Policlinico S. Matteo	Transthyretin amyloidosis	Hulyo 2010	Phase 2
NCT01653522	Ang Cleveland Clinic	Mga Sakit sa Migraine\|Sakit ng Ulo, Migraine\|Migraine\|Sakit ng Ulo\|Migraine na May Aura\|Migraine na Walang Aura\|Mga Sakit sa Ulo, Pangunahin	Hulyo 2012	Hindi Naaangkop
NCT01820910	International Extranodal Lymphoma Study Group (IELSG)	Marginal Zone Lymphoma ng Ocular Adnexal	Marso 2013	Phase 2
NCT01323101	Unibersidad ng Southern California	Cystic fibrosis	Abril 2008	Phase 4
NCT00829764	Teva Pharmaceuticals USA	Malusog	Oktubre 2006	Phase 1
NCT01668498	AIO-Studien-gGmbH	Ras-wildtype Colorectal Cancer	Mayo 2011	Phase 2
NCT01030666	Peter Eickholz\|Pamantasan ng Heidelberg\|Dr. August Wolff GmbH & Co. KG Arzneimittel\|Gaba International AG\|Goethe University	Periodontitis	Abril 2007	Phase 4
NCT00012688	US Department of Veterans Affairs\|Colgate-Periogard-Dentsply\|VA Office of Research and Development	Diabetes Mellitus\|Mahinang Glycemic Control\|Peridontal Disease		Hindi Naaangkop
NCT01885910	Derm Research, PLLC\|WFH MEDICAL, LLC	Acne Vulgaris	Hulyo 2013	Phase 4
NCT02328469	University Medical Center Ljubljana\|Slovenian Research Agency\|University of Ljubljana School of Medicine, Slovenia\|Harvard University	Aseptic Meningitis	Hunyo 2014
NCT00355602	Unibersidad ng Dundee\|Tenovus Scotland	Colitis, Ulcerative	Hulyo 2006	Hindi Naaangkop
NCT02606032	Hamilton Health Sciences Corporation\|Hamilton Academic Health Sciences Organization	Ulcerative colitis	Mayo 2016	Phase 2
NCT01465802	Pfizer	Non Small Cell Lung Cancer (NSCLC)	Disyembre 26, 2011	Phase 2
NCT02623959	MD Anderson Cancer Center	Mga Advanced na Kanser\|Malignant Pleural Effusions	Abril 27, 2016	Phase 4
NCT03481972	IRCCS Policlinico S. Matteo	TTR Cardiac Amyloidosis	Abril 11, 2018	Phase 3
NCT00428818	University of Texas Southwestern Medical Center	Impeksyon	Agosto 2005	Hindi Naaangkop
NCT01935622	Pamantasang Komonwelt ng Virginia	Non-ischemic Cardiomyopathy\|Systolic Heart Failure (NYHA II-III)	Hulyo 2012	Phase 2
NCT01886560	Unibersidad ng Sun Yat-sen	Nasusunog ang Mata	Setyembre 2013	Phase 2\|Phase 3
NCT04239755	Pamantasan ng Damanhour\|Pamantasan ng Tanta	Traumatikong Pinsala sa Utak	Disyembre 15, 2019	Phase 4
NCT02204254	Center Hospitalier Universitaire de Nice	Rosacea	Marso 2014	Hindi Naaangkop
NCT00837213	Stiefel, isang GSK Company\|GlaxoSmithKline	Acne	Agosto 2007	Phase 4
NCT03115177	Rush University Medical Center	Osteoarthritis	Nobyembre 2015	Hindi Naaangkop
NCT03618108	Cadrock Pty. Ltd.\|Center for Digestive Diseases, Australia	Coronary Heart Disease\|Mga Impeksyon sa Chlamydophila Pneumoniae	Abril 4, 2018	Phase 2
NCT03435952	MD Anderson Cancer Center\|BioMed Valley Discoveries, Inc\|Merck Sharp & Dohme Corp.	Malignant Neoplasm of Breast\|Malignant Neoplasms of Digestive Organs\|Malignant Neoplasms of Eye Brain and Other Parts of Central Nervous System\|Malignant Neoplasms of Female Genital Organs\|Malignant Neoplasms of Ill-defined Secondary and Unspecified Sites\|Malignant Neoplasms of Independent Multiple Sites\|Malignant Neoplasms ng Lip Oral Cavity at Pharynx\|Malignant Neoplasms ng Male Genital Organs\|Malignant Neoplasms of Mesothelial and Soft Tissue\|Malignant Neoplasms of Respiratory and Intrathoracic Organs\|Malignant Neoplasms of Thyroid and Other Endocrine Glands\|Malignant Neoplasms of Urinary Tract	Hulyo 10, 2018	Phase 1
NCT01867294	Academic and Community Cancer Research United\|National Cancer Institute (NCI)	Advanced Malignant Neoplasm\|Dermatologic Complication	Agosto 31, 2012	Phase 2
NCT01677286	Unibersidad ng Boston	Amyloidosis	Hulyo 2012	Phase 2
NCT00511875	Thomas Gardner\|Juvenile Diabetes Research Foundation\|Milton S. Hershey Medical Center	Diabetic Retinopathy	Hulyo 2008	Phase 2
NCT04108897	Johns Hopkins University	Rosacea	Setyembre 17, 2019	Maagang Phase 1
NCT00631501	Kaunas University of Medicine\|University Hospital, Linkoeping	Lateral Epicondylalgia (Tennis Elbow)		Hindi Naaangkop
NCT02203682	Unibersidad ng Sun Yat-sen	Graves Ophthalmopathy\|Graves Disease\|Mga Sakit sa Mata\|Mga Sakit sa Thyroid\|Mga Sakit sa Endocrine System\|Mga Sakit sa Mata, Namamana\|Hyperthyroidism\|Mga Sakit sa Autoimmune\|Mga Sakit sa Immune System	Hulyo 2014	Phase 2
NCT02005653	Indian Council of Medical Research	Filarial; Infestation	Pebrero 2009	Phase 4
NCT03585140	Centro Dermatológico Dr. Ladislao de la Pascua	Acne Vulgaris\|Pagbabago sa Diyeta	Enero 1, 2016	Hindi Naaangkop
NCT02147262	University Medical Center Ljubljana\|University of Ljubljana School of Medicine, Slovenia\|Medical University of Vienna\|Harvard University	Talamak na Atrophic Acrodermatitis	Hulyo 2013	Hindi Naaangkop
NCT02220751	Unibersidad ng Sao Paulo\|Fundação de Amparo à Pesquisa do Estado de São Paulo	Periodontitis\|Type 2 Diabetes Mellitus	Marso 2009	Phase 3
NCT01825408	Unibersidad ng North Carolina, Chapel Hill	Sinusitis	Pebrero 2013	Phase 4
NCT02884713	King Faisal Specialist Hospital at Research Center	GASTRITIS	Hunyo 2013	Hindi Naaangkop
NCT02726646	Unibersidad ng Campinas, Brazil\|Pontificia Universidade Catolica de Sao Paulo	Talamak na Periodontitis	Hunyo 2015	Phase 2
NCT00883818	Samsung Medical Center	Overactive na pantog	Enero 2007	Phase 4
NCT00829790	Teva Pharmaceuticals USA	Malusog	Oktubre 2006	Phase 1
NCT01949233	University of Oxford\|Oxford University Hospitals NHS Trust	Marfan Syndrome	Oktubre 2013	Phase 2
NCT01518192	University Medical Center Ljubljana\|Slovenian Research Agency	Erythema Migrans\|Mga Sintomas ng Post-Lyme Disease	Hunyo 2006	Phase 4
NCT02845024	Unibersidad ng Islamikong Azad, Tehran	Diabetes Mellitus na May Sakit na Periodontal	Setyembre 2014	Hindi Naaangkop
NCT01879930	University Hospital Inselspital, Berne	Talamak na Pelvic Pain Syndrome\|Bladder Pain Syndrome	Nobyembre 2012	Phase 4
NCT00041977	CollaGenex Pharmaceuticals	Acne Rosacea	Hunyo 2002	Phase 3
NCT02341209	Rochester General Hospital	Cutaneous T-cell Lymphoma\|Mycosis Fungoides\|Sezary Syndrome	Pebrero 6, 2018	Phase 2
NCT00002872	Eastern Cooperative Oncology Group\|National Cancer Institute (NCI)\|North Central Cancer Treatment Group	Metastatic na Kanser	Nobyembre 1996	Phase 3
NCT03162497	Medikal na Unibersidad ng Vienna	Mga Dry Eye Syndrome\|Meibomian Gland Dysfunction	Enero 8, 2018	Phase 4
NCT01418742	Gesellschaft fur Medizinische Innovation ? Hamatologie und Onkologie mbH\|ClinAssess GmbH	Colorectal Carcinoma	Agosto 2011	Phase 2
NCT00980148	National Institute of Allergy and Infectious Diseases (NIAID)	Impeksyon ng Chlamydial	Disyembre 2009	Phase 3
NCT03342456	Ang Ikatlong Ospital ng Xiangya ng Central South University\|Livzon Pharmaceutical Group Inc.\|Yung Shin Pharm. Ind. Co., Ltd.	Duodenal Ulcer Dahil sa Helicobacter Pylori	Disyembre 13, 2017	Phase 4
NCT04310930	Ang University of Queensland\|Australian Government Department of Health\|Children's Hospital Foundation\|Cystic Fibrosis Foundation\|Newcastle University\|Griffith University\|Erasmus Medical Center\|Monash University\|University of Copenhagen\|Hôpital Cochin\|South Australian Health and Medical Research Institute\|University ng Melbourne\|James Cook University, Queensland, Australia\|Murdoch Childrens Research Institute	Sakit sa Pulmonary Dahil sa Mycobacteria (Diagnosis)	Marso 2020	Phase 2\|Phase 3
NCT03709459	Kirby Institute\|South Australian Health and Medical Research Institute\|Monash University	Pag-iwas sa STI	Disyembre 17, 2019
NCT04067011	Emergent BioSolutions\|Biomedical Advanced Research and Development Authority	Anthrax	Agosto 12, 2019	Phase 2
NCT02844634	British Columbia Center para sa Pagkontrol ng Sakit	HIV\|Syphilis	Mayo 15, 2018	Phase 4
NCT00647959	Mylan Pharmaceuticals	Malusog	Marso 2006	Phase 1
NCT00170222	Medical Center Alkmaar	Chronic obstructive pulmonary disease	Hulyo 2002	Phase 4
NCT03075891	Galderma	Rosacea	Hulyo 5, 2017	Phase 4
NCT00031499	National Institute of Allergy and Infectious Diseases (NIAID)	Syphilis	Hunyo 2000	Phase 3
NCT01205464	Unibersidad ng Linkoeping	Pagkapagod\|Radicular Pain\|Cognitive Dysfunction\|Paresthesia\|Paresis	Pebrero 2005	Hindi Naaangkop
NCT01301586	Nexgen Dermatologics, Inc.	ACNE VULGARIS	Nobyembre 2010	Phase 1\|Phase 2
NCT02305940	Imperial College London	Chronic Obstructive Pulmonary Disease (COPD)	Hulyo 2014	Phase 3
NCT00351182	Dong-Min Kim\|Chosun University Hospital	Scrub Typhus	Setyembre 2005	Phase 3
NCT03334682	Ospital ng Pamantasan ng Nantes	Acne Vulgaris	Enero 31, 2018	Phase 3
NCT01788215	Unibersidad ng Rochester	Polycystic Ovarian Syndrome (PCOS)\|Irregular Menstrual Cycles\|Androgen Excess	Nobyembre 2010	Phase 3
NCT03076281	Sidney Kimmel Cancer Center sa Thomas Jefferson University\|Thomas Jefferson University	Larynx\|LIP\|Oral Cavity\|Pharynx	Abril 3, 2017	Phase 2
NCT00439166	Hamilton Health Sciences Corporation\|The Physicians' Services Incorporated Foundation\|McMaster University	Sakit na Alzheimer	Pebrero 2007	Phase 3
NCT02463942	University Medical Center Ljubljana\|University of Ljubljana School of Medicine, Slovenia	Tick-borne Encephalitis	Setyembre 2014	Hindi Naaangkop
NCT00803842	Northwestern University	Hindi Maliit na Cell Lung Cancer	Oktubre 2008	Hindi Naaangkop
NCT02086591	Unibersidad ng Rochester	Adult Diffuse Large B-Cell Lymphoma\|Paulit-ulit na Mantle Cell Lymphoma\|Lymphoma, Follicular\|Marginal Zone B-Cell Lymphoma\|Malignant Lymphoma - Lymphoplasmacytic\|Waldenstrom Macroglobulinemia\|Small Lymphocytic Lymphoma\|Chronic Lymphocytic Lymphoma (CLLL) Lymphoma	Marso 2014	Phase 2
NCT03980223	University of California, San Francisco\|University of Washington\|National Institute of Allergy and Infectious Diseases (NIAID)\|Mayne Pharma International Pty Ltd\|San Francisco Department of Public Health	Gonorrhea\|Chlamydia\|Syphilis	Nobyembre 26, 2019	Phase 4
NCT00355459	University of Texas Southwestern Medical Center	Dry Eye Syndrome	Agosto 2005	Hindi Naaangkop
NCT01254799	Omar Mamdouh Shaaban\|Assiut University	Pagdurugo ng Uterine	Enero 2008	Phase 3
NCT01547325	NanoSHIFT LLC\|Departamento ng Depensa ng Estados Unidos	Dehisced Surgical Wounds	Mayo 2012	Hindi Naaangkop
NCT00653380	Par Pharmaceutical, Inc.\|Anapharm	Upang Matukoy ang Bioequivalence Sa ilalim ng mga Kondisyon ng Pag-aayuno	Setyembre 1999	Phase 1
NCT00635609	Warner Chilcott	Acne Vulgaris	Marso 2008	Phase 4
NCT03765931	Institut de Recherche pour le Development	Lagnat	Hulyo 2016	Phase 4
NCT01160640	Harold Wiesenfeld\|National Institute of Allergy and Infectious Diseases (NIAID)\|University of Pittsburgh	Pelvic Inflammatory Disease	Nobyembre 2010	Phase 2
NCT01756833	Unibersidad ng Maryland, Baltimore\|National Institute on Aging (NIA)	Aneurysm	Mayo 2013	Phase 2
NCT00688064	Galderma	Malubhang Acne Vulgaris	Agosto 2008	Phase 3
NCT01320033	Galderma	Acne Vulgaris	Marso 29, 2011	Phase 2
NCT03397004	St. Michael's Hospital, Toronto\|Barrow Neurological Institute\|Duke University\|Feinstein Institute for Medical Research\|University of Pittsburgh\|Sunnybrook Health Sciences Center	Hereditary Hemorrhagic Telangiectasia (HHT)	Setyembre 12, 2018	Phase 2
NCT01635530	Ospital ng Turku University	Lyme Neuroborreliosis	Agosto 2012	Phase 4
NCT03727620	Unibersidad ng Mohammed V Souissi	Agresibong Periodontitis	Enero 6, 2014	Phase 1\|Phase 2
NCT02688738	Rothman Institute Orthopedics	Propionibacterium	Marso 2015	Hindi Naaangkop
NCT00358462	Unibersidad ng Washington\|National Institute of Allergy and Infectious Diseases (NIAID)	Urethritis	Enero 2007	Phase 3
NCT02864550	British Columbia Center para sa Pagkontrol ng Sakit	Syphilis\|Mga Impeksyon na Naililipat sa Sekswal	Agosto 15, 2019	Phase 4
NCT01595594	Unibersidad ng Sao Paulo\|Fundação de Amparo à Pesquisa do Estado de São Paulo	Periodontal Disease\|Type 2 Diabetes	Marso 2010	Phase 3
NCT00964834	PharmAthene, Inc.\|National Institutes of Health (NIH)\|Medarex\|Quintiles, Inc.\|Department of Health at Human Services	Anthrax	Hulyo 2009	Phase 1
NCT01809444	Unibersidad ng Sun Yat-sen	Thyroid Associated Opthalmothies	Nobyembre 2012	Phase 2\|Phase 3
NCT01590082	MD Anderson Cancer Center\|National Institutes of Health (NIH)\|National Cancer Institute (NCI)	Melanoma	Nobyembre 2012	Phase 1\|Phase 2
NCT00207584	Mga Sentro para sa Pagkontrol at Pag-iwas sa Sakit	Mycoplasma Pneumoniae	Enero 1994	Hindi Naaangkop
NCT00775177	Ranbaxy Laboratories Limited\|Ranbaxy Inc.	Malusog	Hunyo 2005	Hindi Naaangkop
NCT03462329	University Medical Center Ljubljana	Erythema Migrans	Hunyo 1, 2018	Hindi Naaangkop
NCT00000403	Indiana University\|National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)\|National Institute on Aging (NIA)	Osteoarthritis	Setyembre 1996	Phase 3
NCT03508232	Unibersidad ng Alberta\|Royal Alexandra Hospital	ST Segment Elevation Myocardial Infarction\|Pagkabigo sa Puso	Enero 6, 2020	Phase 2
NCT02553473	Sorlandet Hospital HF	Neuroborreliosis, Borrelia Burgdorferi	Oktubre 2015	Phase 3
NCT02207556	Medikal na Kolehiyo ng Wisconsin	Pangunahing Systemic Amyloidosis	Oktubre 1, 2014	Phase 2
NCT01783106	Royal Liverpool University Hospital\|National Association for Colitis and Crohn's Disease\|National Institute for Health Research, United Kingdom	Sakit ni Crohn	Pebrero 1, 2014	Phase 2
NCT00353743	Hospital de Clinicas de Porto Alegre	Aborsyon, Septic	Mayo 2006	Hindi Naaangkop
NCT01727973	Unibersidad ng Sun Yat-sen	Graves Ophthalmopathy\|Graves Disease\|Mga Sakit sa Mata\|Mga Sakit sa Thyroid\|Mga Sakit sa Endocrine System\|Mga Sakit sa Mata, Namamana\|Hyperthyroidism\|Mga Sakit sa Autoimmune\|Mga Sakit sa Immune System	Oktubre 2012	Phase 1\|Phase 2
NCT00857038	Medical Center Alkmaar\|Leiden University Medical Center\|University of Amsterdam	Talamak na Obstructive Pulmonary Disease\|Pamamamaga\|Pulmonary Emphysema	Abril 2009	Phase 4
NCT02774993	National University Hospital, Singapore\|Tan Tock Seng Hospital\|National University, Singapore\|A*Star	Tuberkulosis	Setyembre 2015	Phase 2
NCT03474458	IRCCS Policlinico S. Matteo	Cardiac AL Amyloidosis	Pebrero 11, 2019	Phase 2\|Phase 3
NCT02874430	Sidney Kimmel Cancer Center sa Thomas Jefferson University\|Thomas Jefferson University	Breast Carcinoma\|Endometrial Clear Cell Adenocarcinoma\|Endometrial Serous Adenocarcinoma\|Uterine Corpus Cancer\|Uterine Corpus Carcinosarcoma	Hunyo 8, 2016	Phase 2
NCT00016835	Unibersidad ng Michigan\|National Institute of Dental and Craniofacial Research (NIDCR)	Sakit sa Periodontal\|Diabetes Mellitus, Type 2	Oktubre 17, 2001	Phase 2
NCT00064766	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	Pagdurugo ng Endometrial\|Periodontal Disease	Pebrero 2003	Phase 4
NCT00803452	Unibersidad ng Louisville	Blepharitis	Hulyo 2008	Phase 4
NCT01434173	Bayer\|RTI Health Solutions	Pinsala sa Atay na Dahil sa Droga	Hulyo 2001
NCT00126204	Barnes-Jewish Hospital	Aortic Aneurysm	Marso 2004	Hindi Naaangkop
NCT01917721	Hawaii Pacific Health	Sakit sa Kawasaki\|Coronary Aneurysm	Oktubre 2013	Phase 2
NCT02775695	Medikal na Kolehiyo ng Wisconsin	Resectable Pancreatic Cancer	Abril 3, 2017	Phase 2
NCT03824340	Ospital ng Aljazeera	kawalan ng katabaan	Enero 30, 2019	Hindi Naaangkop
NCT01847976	Ottawa Hospital Research Institute\|Canadian Breast Cancer Foundation	Sakit	Agosto 2013	Phase 2
NCT02850913	Makerere University\|University of Oxford	Mga seizure	Setyembre 5, 2016	Phase 2
NCT00764361	NanoSHIFT LLC	Ulcer sa Paa ng Diabetic	Enero 2009	Phase 2
NCT02036528	Royer Biomedical, Inc.	Mga Ulser sa Paa ng Diabetic	Enero 2014	Phase 1\|Phase 2
NCT01661985	Ostergotland County Council, Sweden\|Statens Serum Institut	Urethritis\|Cervicitis\|Infection ng Genital Mycoplasma\|Chlamydia Trachomatis	Pebrero 2010	Phase 4
NCT01380483	Par Pharmaceutical, Inc.\|Anapharm	Upang Matukoy ang Bioequivalence Sa ilalim ng mga Kondisyon ng Pag-aayuno	Enero 2000	Phase 1
NCT00648180	Mylan Pharmaceuticals	Malusog	Hulyo 2005	Phase 1
NCT01426269	Galderma Laboratories, LP	Rosacea	Setyembre 2011	Phase 4
NCT02753426	Unibersidad ng California, San Francisco	Talamak na Sakit sa Bato\|Cardiorenal Syndrome	Abril 2016	Phase 1
NCT02583282	Postgraduate Institute ng Medikal na Edukasyon at Pananaliksik	Malignant Pleural Effusion	Agosto 1, 2015	Hindi Naaangkop
NCT02927496	Ang Task Force for Global Health\|United States Agency for International Development (USAID)	Lymphedema\|Lymphatic Filariasis\|Filariasis	Hunyo 19, 2018	Phase 3
NCT00652795	Par Pharmaceutical, Inc.\|Anapharm	Upang Matukoy ang Bioequivalence Sa ilalim ng mga Kondisyon ng Pag-aayuno	Hulyo 2004	Phase 1
NCT03956212	University Medical Center Ljubljana\|University of Ljubljana School of Medicine, Slovenia	Erythema Migrans	Hunyo 1, 2017	Hindi Naaangkop
NCT00855595	Bayer	Papulopustular Rosacea	Pebrero 2009	Phase 4
NCT03457636	Derm Research, PLLC	Acne	Marso 19, 2018	Phase 4
NCT02894268	Sir Run Run Shaw Hospital	Impeksyon ng Helicobacter Pylori	Pebrero 2016	Phase 4
NCT03465774	MD Anderson Cancer Center\|National Cancer Institute (NCI)	Malignant Pleural Effusion	Marso 8, 2018	Maagang Phase 1